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First HIV-Positive-to-HIV-Positive Lung Transplant Signals a New Frontier

HIV阳性肺移植首获成功

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A lung transplant from an HIV-positive donor to an HIV-positive recipient marks a historic first in medicine. Not long ago, such an idea was unthinkable. During the early HIV epidemic, people living with the virus faced severe stigma, and organ transplants were often denied to them. With the advent of effective antiretroviral therapy, HIV became a manageable chronic condition. However, many patients still develop organ failure over time. Yet, organs from HIV-positive donors were still discarded, fearing new infections or complications.

The landscape began to shift with the 2013 HIV Organ Policy Equity (HOPE) Act in the United States, which allowed research into transplants between HIV-positive individuals. Successful kidney and liver transplants soon followed in 2016, conducted under strict protocols. Their outcomes were comparable to those using HIV-negative organs. Over time, regulatory bodies relaxed restrictions for abdominal organs, but heart and lung transplants from HIV-positive donors remained labeled experimental. The recent lung surgery challenges that cautious approach, breaking new ground.

Inspired by Scientific American reporting · Rewritten by Vocabsavvy · Vocabsavvy Original (inspired-by attribution)

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